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Recommendation
Radiation therapy to the chest wall after mastectomy #1
For patients with breast cancer who have undergone a mastectomy and have at least four positive lymph nodes and a T3 or T4 tumour or involved surgical margins, offer adjuvant radiation therapy to the chest wall.
Offer adjuvant postmastectomy radiotherapy to people with node-positive (macrometastases) invasive breast cancer or involved resection margin
How this guidance was developed
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This recommendation was adapted from the NICE 2018 guidelines (UK). The source recommendation is based on a systematic review of the evidence conducted to September 2017 and used wording (‘Offer’) indicative of a strong recommendation (using GRADE methods) by the source guideline authors. The source recommendation was adapted by narrowing the population to ‘patients who have undergone a mastectomy and have at least four positive nodes and a T3 or T4 tumour or involved surgical margins’ as there is clear evidence in patients with locally advanced disease. |
Radiation therapy to the chest wall after mastectomy #1
Recommendation
For patients with breast cancer who have undergone a mastectomy and have at least four positive lymph nodes and a T3 or T4 tumour or involved surgical margins, offer adjuvant radiation therapy to the chest wall.
Principles in action
Safe and quality care
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This recommendation was adapted from the NICE 2018 guidelines (UK). The source recommendation is based on a systematic review of the evidence conducted to September 2017 and used wording (‘Offer’) indicative of a strong recommendation (using GRADE methods) by the source guideline authors. The source recommendation was adapted by narrowing the population to ‘patients who have undergone a mastectomy and have at least four positive nodes and a T3 or T4 tumour or involved surgical margins’ as there is clear evidence in patients with locally advanced disease. |