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Recommendation
Pregnancy considerations
Premenopausal women should be counselled regarding the risk of becoming pregnant while on chemotherapy, endocrine therapy, anti-HER2 therapy, or during radiation therapy, even in the presence of amenorrhoea.
All young women should be counselled regarding the risk of getting pregnant while on chemotherapy, endocrine or anti-HER-2 therapy, despite developing amenorrhea, and of the need for adequate non-hormonal contraception if they are sexually active and could become pregnant
Strong recommendation, moderate quality evidence. Strong recommendation, can apply to most patients in most circumstances without reservation
How this guidance was developed
This recommendation was adopted from the ESO-ESMO 2017 guidelines for breast cancer in young women (Europe), and which remained unchanged in the 2020 updated guidelines. The source recommendation is based on a non-systematic review of the evidence (date was not reported) discussed by the source guideline authors in November 2016 and October 2018 and graded ‘strong’ (using ACCP/Adapted Infectious Diseases Society of America-United States Public Health Service Grading System methods). The source recommendation was adapted to include 'radiation therapy' as a risk factor and minor stylistic changes were made.
Related guidance by topic
Pregnancy considerations
Recommendation
Premenopausal women should be counselled regarding the risk of becoming pregnant while on chemotherapy, endocrine therapy, anti-HER2 therapy, or during radiation therapy, even in the presence of amenorrhoea.
Principles in action
Patient-centred care
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Supportive care
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Communication
This recommendation was adopted from the ESO-ESMO 2017 guidelines for breast cancer in young women (Europe), and which remained unchanged in the 2020 updated guidelines. The source recommendation is based on a non-systematic review of the evidence (date was not reported) discussed by the source guideline authors in November 2016 and October 2018 and graded ‘strong’ (using ACCP/Adapted Infectious Diseases Society of America-United States Public Health Service Grading System methods). The source recommendation was adapted to include 'radiation therapy' as a risk factor and minor stylistic changes were made.
Related guidance by topic
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Reproductive and sexual health
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